320. What Ibogaine Does to a Damaged Brain - Jonathan Dickinson

“And I think part of it was because they were looking at it for treating opioid use disorder. And then here was coming buprenorphine and Suboxone and it provided a solution that sort of resolved the long-term overdose risk.”

Also filed under Buprenorphine

“That's that's witchcraft. And that's it. Yeah. I mean, you know, actually, it's a lot harder for us when we, when somebody wants to stop taking Suboxone now to help them come off of it because it's so long acting and you can't give Ibogaine while there's still suboxone in the system.”

“Suboxone makes it, it's a like they call it liquid handcuffs, that and methadone for a reason because it's very difficult and painstaking to come off of them. Right. And it's a long, long titration period. Long period of withdrawal compared to what you would get even from heroin or oxycontin, which is more compact and shorter.”

“She's fine. Yeah. Yeah. If it's managed properly and if it's used like short term, Suboxone can actually be an effective way to detox off of other substances. You know, if you take it for a short time and you taper down. But anyways, that's not really the interest of physicians.”

“Mm-hmm. You know, opioid epidemic has played out. Right. Suboxone was there the entire time. Mm-hmm. You know? The standard of care did not help to mitigate the intense devastation of that, you know, whole period. Right? So, there's a whole bunch of, uh, whole bunch of reasons that have sort of culminated in this openness and this willingness to explore that.”

“have been a contributor to the opioid epidemic. You're also not allowed to take people off of Suboxone or methadone. Wow. Right. So you can't do a study where you look at the effect of ibogaine and hoping to effectively taper people off of those medications because you're potentially exposing them to fatal overdose risk if they're not on those medications anymore.”

“It comes in little capsules. We're giving IVs of magnesium to help protect the heart and prepare the body, a lot of fluids before that. And then once they start taking the Ibogaine, they actually are around a campfire.”

“Ibogaine. Part of it was sort of packaging it with this idea that people are taking magnesium around the same time. And so, that sort of opens up the conversation about: hey, yes, there's QT prolongation, there's cardiac risk, but there's ways, there's strategies to be able to manage it.”

“Suboxone makes it, it's a like they call it liquid handcuffs, that and methadone for a reason because it's very difficult and painstaking to come off of them. Right. And it's a long, long titration period. Long period of withdrawal compared to what you would get even from heroin or oxycontin, which is more compact and shorter.”

“have been a contributor to the opioid epidemic. You're also not allowed to take people off of Suboxone or methadone. Wow. Right. So you can't do a study where you look at the effect of ibogaine and hoping to effectively taper people off of those medications because you're potentially exposing them to fatal overdose risk if they're not on those medications anymore.”

“So if you see these lengthening cure intervals, you can address that. Yeah. So like in over 4,000 treatments, I think we've had to deliver atropine 15 times for like asymptomatic bradycardia, like way before you would see something develop into a problem.”

“Yes, I've got a book that's coming out today. It's Ibogaine and the Bicameral Mind. We had them on today. The timing was great Why didn't we have it here. Did you bring a copy of it?”

“painstaking to come off of them. Right. And it's a long, long titration period. Long period of withdrawal compared to what you would get even from heroin or oxycontin, which is more compact and shorter. Right. So, and I found that to be true in my wife's journey too.”