Mentioned 4 times on 1 show. Most recently heard 31/08/2026.
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“And so there was like that aha moment. And that's what led to the class of what are known as CGRP antagonists. And the CGRP antagonists are kind of broken down into two buckets. One are what are called large monoclonal antibodies, which is the medication that our patient was placed on.”
“These are drugs that are administered intravenously at what frequency? The CGRP antagonists, the large monoclonal antibodies, three of them are self-injection medications, almost like EpiPens. And those medications have a long half-life.”
“Super interesting. You mentioned the oral equivalent of these as well. Yes. So there are oral medications that are known as GPANs that are small molecule CGRP antagonists. These medications have shorter half-lives and there are fewer of them.”
“Once again, that's in the class that we were talking about, that CGRP antagonist. Those bioavailabilities are higher. And so that's where somebody may end up getting faster relief.”