Mentioned 2 times on 2 shows. Most recently heard 08/09/2026.
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“to tolerate. It turned out when I was doing the deep dive in the medical literature that spironolactone, a drug they use for women with PCOS to lower testosterone, and Dipyridamol persantine, a drug that's used to stop strokes with transient ischemic attacks.”
“enough to be clinically significant. Usually caffeine is put into formulations with other things like ketoconazole that are also weak antiandrogens. Of note, spironolactone can be prescribed topically, but it is absorbed. Systemically, because the size of the molecule. So unless your doctor specifically prescribes that for you, especially as a male, do not use topical spironolactone.”