Mentioned 2 times on 1 show. Most recently heard 01/06/2026.
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“called Trazodone. Trazodone was originally developed as an antidepressant approved at doses of 300 milligrams for major depressive disorder. But approximately half of the patients taking Trazodone for depression develop excessive daytime sleepiness compared to 19% of those receiving a placebo.”
“it's prescribed for depression. It's popular because it's inexpensive, it's not controlled, and it's quite safe. A 2022 meta-analysis confirmed that it increases total sleep time and that it has a very favorable property that most sleep medications don't. It increases slow wave N3 sleep rather than suppressing it, with minimal effects on other aspects.”