“of over 12,000 people. And vitamin D reduced dementia risk by around 33% in adults with mild cognitive impairment and also had APOE4. This is a key genetic risk factor for neurodegenerative diseases.”
“The other 40% or so has levels that's known as insufficient. So these are people that have vitamin D levels above 20 nanograms per milliliter, but they're below 30 nanograms per milliliter. And there's really a simple solution to avoiding this deficiency and insufficiency, and that is a vitamin D supplement. Usually people that are vitamin D deficient, if they take around”
“make vitamin D. And then also just body fat. So vitamin D is actually a fat-soluble vitamin, and it's stored in fat. And so the more body fat that you have, that means the less vitamin D3 is bioavailable to be released into the bloodstream, where that it undergoes further metabolic conversion to the body.”
“low vitamin D levels and dementia risk. Many different studies have found this same association. And so one might say, well, people that are vitamin D deficient might just be less healthy. They might be going out in the sun less.”
“low vitamin D levels. In other words, you just look at someone's genes. And if they have a certain variation of that vitamin D converting gene that makes it not as effective, you put them into the low vitamin D group because we know people with those genes actually do have low vitamin D.”
“for example, for dementia and Alzheimer's disease. And so what's been shown is that genetically low vitamin D levels increase dementia risk by up to 54%. Again, this is really confirming that observational data, which really can't really show causation. And so it strengthens that data,”
“brain's communicating. So when you have damage to that white matter, it really does affect cognition. It affects communication and memory. For every 10 nanomole per liter increase in vitamin D, there was a small decrease in the volume of these white matter hyperintensities, suggesting that having higher levels of vitamin D can protect against this type of brain damage.”
“data out there, particularly when it comes to vitamin D supplementation affecting cognition in normal, healthy adults. But there have been a few trials that have actually looked at vitamin D supplementation in people with either Alzheimer's disease or people with mild cognitive impairment.”
“if they took around 800 IUs of vitamin D daily for a year, they had significant improvements in multiple areas of cognition memory, attention, overall IQ. And the same goes with the Alzheimer's disease study. So people”
“So this data, again, really strengthens the argument that low vitamin D can increase dementia risk and that supplementing with vitamin D can help lower that risk, which brings us back to this recent study where vitamin D supplementation was associated with a 40% lower risk of dementia. So let's dive into that a little bit closer.”
“D, it didn't matter what form. And then the other group it was divided into is those that did not take any form of vitamin D supplement. There was a 10-year follow-up, and during that period, supplementing with vitamin D was associated with a 40% lower incidence of dementia.”
“Supplementing with vitamin D was also associated with a greater five-year dementia-free survival. So 84% of adults in the vitamin D group were free of dementia during this time period, while only 68% of the non-vitamin D users were dementia-free during that same period.”
“dementia risk among all groups, there were several interesting findings regarding the benefits of vitamin D for certain populations. So for example, women derived the greatest benefit from vitamin D. They actually experienced less dementia compared to men who supplemented. And while vitamin D”
“different mechanisms by which vitamin D can support brain health. And again, it's pretty simple to get a vitamin D test and to take a relatively inexpensive vitamin D supplement as well.”
“is also going to block out the ability to produce vitamin D3 in our skin. That includes sunscreen. It also includes skin pigmentation. So melanin, this is the darker pigmentation that's a natural sunscreen.”
“two groups, those who reported using vitamin D supplements in any form. It could be calcium, vitamin D, it could be the active form of vitamin D, it could be vitamin D2. So any form of vitamin D, it didn't matter what form. And then the other group it was divided into is those that did not take any form of vitamin D supplement.”
Also filed under Vitamin D
“So living in a northern latitude, many months of the year, actually, there's no UVB radiation even reaching the atmosphere.. So people that are living in more northern latitude areas are not able to make vitamin D3 in their skin from the sun for many, many months out of the year. So that also really affects the ability to make vitamin D.”
Also filed under Vitamin D
As referenced on air, with the quote and the moment. Reported, not evaluated.
“A new study found that vitamin D supplementation was associated with a 40% lower risk of dementia over a decade. After just five years, 84% of the vitamin D supplement users were dementia-free compared to 68% of the non-users. This was a study of over 12,000 people.”
“I mean, there are many, many, many what are called observational studies that are looking at a correlation between low vitamin D levels and dementia risk. Many different studies have found this same association.”
“there's many different genes that regulate the ability of your body to produce vitamin D3 and convert it into the steroid hormone... genetically low vitamin D levels increase dementia risk by up to 54%”
“So for example, with these observational studies, we can look at what's called Mendelian randomization. This is a way to use genetics to look at how something in the environment can affect an outcome.”
“And so what's been shown is that genetically low vitamin D levels increase dementia risk by up to 54%.”
“So there have been studies that have shown that have looked by fMRI at what's called white matter hyperintensities. So these kind of show up as little white hyper spots, if you're looking at a MRI image of the brain.”
“there have been studies that have shown that have looked by fMRI at what's called white matter hyperintensities... For every 10 nanomole per liter increase in vitamin D, there was a small decrease in the volume of these white matter hyperintensities”
“So in both those scenarios, in people with mild cognitive impairment, if they took around 800 IUs of vitamin D daily for a year, they had significant improvements in multiple areas of cognition and memory.”
“in people with mild cognitive impairment, if they took around 800 IUs of vitamin D daily for a year, they had significant improvements in multiple areas of cognition and memory”
“And the same goes with the Alzheimer's disease study. So people that took, again, 800 IUs a day for over a year, and these people were already diagnosed with Alzheimer's disease, they also had improved scores on memory and attention tests.”
“people that took, again, 800 IUs a day for over a year, and these people were already diagnosed with Alzheimer's disease, they also had improved scores on memory and attention tests... there was also a reduction in blood biomarkers of amyloid beta pathology, such as amyloid beta-42”
“So the study included 12,388 adults who were divided into two groups, those who reported using vitamin D supplements in any form.”
“The study included 12,388 adults who were divided into two groups, those who reported using vitamin D supplements in any form... There was a 10-year follow-up, and during that period, supplementing with vitamin D was associated with a 40% lower incidence of dementia.”
“This was a randomized controlled trial. Those individuals that took vitamin D also had decreased levels of various markers of oxidative stress compared to people that were given the placebo.”