B Vitamins

“Exactly. And you want it, you want to metabolize. You want to see if you're metabolizing appropriately, if you're deficient in certain vitamins, because maybe it's a simple B vitamin that you need to help regulate how your hormones are metabolizing and where your progesterone is, where everything else is.”

“correct? Well, or a healthy diet. So, I mean, I think if you have a well-balanced diet and a lot of the food is now supplemented with, you know, B vitamins and folic acid and things that you want to be replete in with pregnancy.”

“What do you think are the biggest wastes of money that people spend on longevity? Oh, well, the overdosing of vitamins, particularly B vitamins. I think that if you're on a vegan diet, yeah, you should make sure you're not deficient in any B vitamins.”

“Some people do that. I think, yeah, you'll get a short-term hit. But I nibble on my B vitamins. I don't take the whole thing. I tried, again, the self-experimentation over the last couple of years recovering from this, this mold complex illness stuff has been interesting to say the least.”

“So I did a bunch of genetic testing, came back, I've got four different polymorphisms that make me suck at B vitamins, like one in the blood, one in the brain, one in the methylation, and one in something else. One of the potential put forward explanations was, well, your mean collicular volume, your MCV is high.”

“B12, like 500 micrograms. You tiny, teeny, tiny little dot. It's almost like got to put a huge needle in your leg to put this teeny, tiny amount of B vitamins in. I didn't realize that you can get something if you push it too far called B12-induced confusion.”

“was trying to push back against. What I'm saying is, I know what happens when you push B vitamins too far. And I actually did that the week. It was the biggest week of the show last year where I had Rogan. I was on Rogan on the Thursday and then recorded with Naval Ravicount on the Saturday.”

“So like with almost any pharmaceutical, the oral contraceptive depletes certain micronutrients, magnesium, there's certain vitamin Bs that are depleted. It also affects the microbiome.”

“So if you are deficient in the complex of B vitamins, you're deficient in methylfolate, you're deficient in trimethylglycine, TMG, then your body can now take selenium, which comes into the body.”

“that I've made them use more of the B vitamins. So let's just pause there. So you're saying that by asking your patients to take more vitamin D, you're saying that the body has also started to use more B vitamins, which means that by taking more vitamin D, they're now deficient in B vitamins.”

“And they live. It turns out that the eight B vitamins were first described as bacterial growth factors. They are chemicals that one bacteria is able to make, and it pushes it out of itself into the environment.”

“But here I am back again with one big question. These two women with the burning in their hands and feet, why did they get B vitamin deficient? If the Bs come from the food, they've had the same diet all along.”

“our cats and dogs that we keep inside. So to summarize for me, what is the link between vitamin D and the B vitamins? It turns out that all the Bs come from the microbiome. Yes. Okay. I understood that. In order to have the correct microbiome, we are actually commensal organisms with our microbiome.”

“Taking vitamin D supplements will not drain your body's B vitamins. Let me read my title. Vitamin D deficiency changes the intestinal microbiome, reducing B vitamin production in the gut. The resulting lack of pantothenic acid adversely affects the immune system, producing a pro-inflammatory state associated with atherosclerosis and autoimmunity.”

“the parallel epidemics of abnormal sleep and abnormal intestinal microbiome are linked to one another through vitamin D deficiency. Proper supplementation doses of vitamin D plus all eight B vitamins appears to return the intestinal microbiome to normal in three months. Reinstating the normal microbiome not only treats IBS symptoms, it returns the supply of vitamin Bs to their natural daily doses.”

“good for us, not unnecessary. They are good for the person who needs them, and only until the normal source picks up again. Both sleep disruption and pain can be caused by large doses of B vitamins once the intestinal microbiome has returned to normal. So it's not the case that the B vitamins are very biologically intertwined, both in their intestinal production and cellular use.”

“involved and the B vitamins involved in methylation. So particularly B12 and folate also potentially B6 and riboflavin, although that might depend a little bit more on, on the individual. Then there are some other nutrients that, you know, have some pretty good evidence for them.”

“B vitamins, the normal range might go up to like 15 or 16. But we know that risk is definitely elevated above 13, and is probably elevated above sort of 10 to 11. So what your target range really might be is it's probably lower than what the normal range might be.”

“cognitive decline. That is particularly the case for omega-3s and B vitamins that lower homocysteine. And so this is the interactions that you were talking about earlier. And this is the best one that we know of, although I'm sure there are many more.”

“status and B vitamin status interact, and they're dependent on one another. So if you give B vitamins to somebody who has elevated homocysteine, you bring down their homocysteine, but they have poor omega-3 levels, you don't see any benefit. And that's been shown in the data.”

“before you can decide how to treat it. But in this human mind, when we're creating these neurotransmitters and we're not breaking them down, the question is what in that chart breaks down these neurotransmitters? Well, that specific complex of B vitamins, a very specific form of B12 called methylcobalamin, in a refined form of folate called methylfolate.”

“But those forms of B12 exacerbate anxiety. So hydroxycobalamin, the entire complex of B vitamins that I showed you right here, a specific form of folate called methylfolate or folinic acid. In fact, the US FDA just approved the first nutrient as a prescription.”

“itself as well. So I think from a minerals and vitamins standpoint, the low hanging fruits are typically going to be like B vitamins, but in particular, like from a mineral side, you know, you have, you know, magnesium, zinc, and the vitamin D3 are going to be three things that specifically on top of the minerals”