Growth Hormone

“if you're allowed to be you should definitely be on testosterone and definitely be on some sort of uh human growth hormone either something that pumps it up like sermorelin which like naturally makes your body produce more testosterone or more uh human growth”

“paper aimed at thymic regeneration. And it was a little bit of a kitchen sink approach, right? They gave these patients growth hormone and metformin and a whole cocktail of things. And on imaging, they showed, hey, look, these, you know, these in the patients who got this, and by the way, it was even worse because I think it was an open label study, so there wasn't even a randomization.”

“Because I don't even recall the rationale for metformin growth hormone and DHEA or whatever they were giving. Have you followed this space at all? And are there molecular attempts at this?”

“do, you know, I do whatever, testosterone and human growth and all that kind of stuff. So it does make my muscles stronger because I was doing things.”

“They've always spiked my PSA. I, I just, for me, they don't, they don't tend to work. Um, I am curious about, but I, I don't think I'm old enough yet to really embark on a somatotrope growth hormone experiment. But the clinical trial by exploring low-dose growth hormone for people.”

“That distinction matters a lot for CJC1295 because its appeal rests on stimulating the growth hormone pathway. And we already have a much more direct way to interrogate that pathway, giving growth hormone itself.”

“But in growth hormone-replete adults, i.e., virtually everybody listening to this podcast, including me, the results have been surprisingly underwhelming.”

“We already know what happens when we push this pathway more directly. If directly administering growth hormone has largely failed to produce meaningful functional benefits in growth hormone-replete adults, the burden of proof is high for claiming that an indirect growth hormone-releasing hormone will produce dramatically different results.”

“Everything came from Germany, I think. I think they were getting— Decarobalin, all that shit. I think they were getting human growth hormone from cadavers. See if that's true. Jamie, put that into our AI-sponsored perplexity. Did they used to get human growth hormone from cadavers?”

“I think they did. I think that's how they used to get it. What do you get human growth hormone from now? That's a good question. I don't know. I don't know how they do it. It's synthetic. I know it's synthetic. So it must be they isolate the molecule, they figure out how to reproduce it, and then they make it somehow.”

“I have no idea. But the way they used to do it back then, cadaver-derived human growth hormone was real used mid-1900s to 1985. It turned out to be dangerous because it sometimes transmitted prion diseases like Creutzfeldt-Jakob, and is no longer used.”

“But, yeah, Brian—I don't believe that Brian's growth hormone is the same as yours and mine. What does that mean? It might be molecularly different, or it might have—you're going to have to talk to Ryan.”

“But it's— His growth hormone is different? Yeah. He's a different kind of growth hormone? He has a mutation in his growth hormone. Well, that makes sense. Yeah, it does. I mean, he's almost seven feet tall, and he's 400 pounds. Yeah, and he—and he doesn't stop.”

“Oh, he's so loud. And he's open about all the sauce that he's on. He's on everything. I mean, someone, who was in here that was explaining how much growth hormone he takes? I heard he debunked that. Oh, really? I saw a video where he said it wasn't true.”

“Also growth hormone is very expensive. Very expensive. Yeah. Like Pfizer's pens are in the thousands of dollars. So like if you want, if you're rich, you can afford to, you know, have a growth hormone habit, but otherwise a secretagogue costs, you know, less than a hundred bucks. I'm told that growth hormone doesn't shut down one's own production.”

“With Tirzepatide or Retatrutide, whatever it may be, and then using a growth hormone modulation. If you can afford growth hormone or Tesamorelin, Ipamorelin. And you're seeing people lose a lot of fat. Gain a lot of muscle in short amounts of time. Is that healthy? We'll find out. But that is like the celebrity protocol.”

“I'd say there are better ways to do it. Like, not that I'm endorsing any intervention like this, but you'd be better off just focusing on growth hormone than you would injecting yourself with insulin. So I am not a fan. Now, I appreciate some big yoked bodybuilder looking at relatively svelte, small Ben Bickman and saying, well, what do you know?”