Wine

“Easy to hang out with, man. Like, easy. Said he spent 30 grand a month on wine. Also, when they were like, when they're doing that trial, they're like, was this vial for Coke? And he goes, yeah.”

“Yeah, but the thing is. What does this have to do with my divorce? Yeah, I do blow, bro. If you get to a fucking crazy baller wine collector status, that could be one bottle. What were they saying? It was like a super mega drink or something. It was during the trial where they're like, and Johnny had one of his super mega drinks of wine.”

“With consumption, then the risk went down a bit. One glass of wine per day for women, two glass of wine per day for men. But then the U comes back up. So we thought there was a sweet spot. And it turns out that reassessing that indicates that really any alcohol consumption is probably not good for the brain.”

“You know, have a glass of red wine. We know that many people in the blue zones, for example, will drink some wine, as do I from time to time. But I find it threatening. Alcohol itself is a neurotoxin. And I think it's, let's get our polyphenols from what you just described, what you just showed, from coffee and extra virgin olive oil.”

“Like, I'm not one of those guys that's like, don't drink alcohol on Thanksgiving with your family. Like, no, no, enjoy your wine, enjoy this. I'm speaking mostly to the stuff that is a waste of time. So, there is some value to alcohol, right? Yes, it has calories, but when I'm having a glass of wine with my uncle or my cousin who I haven't seen”

“I would say alcohol is kind of a shit drug in terms of the good versus the bad. I'd like a glass of wine with dinner or something. But beyond that, the trade-offs go way down. Like the second, third, like you're not improving your enjoyment of the evening. No.”

“And then I went out with my wife and had a, I think I had a margarita. Margarita or a glass of wine, something like that. And then I was like, oh, I think I'm back. Yeah. I like it. See, that's my problem. I can't have a little of something. That's the big problem. And that's why drinking was kind of easy.”

“aspect. There's a funness to a glass of wine or, you know, a glass of whiskey. But the thing is, just understand what you're doing and don't fuck your body up and try to do your best.”

“had a glass of wine and the next three days were ruined. Okay. And that to me, I mean, in his circumstance, I'm sure that's true. Like, if you have not drank any alcohol for a very long time and you have just a little, I could see how it can have effect.”

“where I was like, fuck man, I should have a glass of wine just right now, even though I don't usually drink. And in fact, I think the alcohol question is a good microcosm to zoom in on. So we've all stopped drinking, apparently.”

“fuck, I kind of want the opposite. Like, I don't barely drink at all, like a glass of wine once a month, maybe. Like, do you know what? I should start just on the weekends, get a glass, maybe two.”

“after one glass of wine and by 24% after two glasses of wine and by almost 40%, 39.2% after three or more glasses of wine or an equivalent amount of alcohol.”

“there a dose dependence there it significantly does there is a dose dependence in general i would not recommend more than uh three to four you know standard drinks uh one huge glass of wine is probably”

“Less is more. Yeah, it's not forbidden. So you can have a glass of wine with your family when you're 11, 12 years old. You know, it's not that big a deal. That Protestant culture we have is very rigid. It's like, don't do this or you're going to die.”

“And it's like, well, no. And maybe, but also, it's maybe pretty nice to have a glass of wine. It's nice to laugh with friends and it's nice, like that's important too in life. And I think balance, we can, you tip the scale one way if you're totally extreme and then you're just like the social life and you're, you know, can't, you know, go out and like, you know, really enjoy yourself for a second.”

“You're not sleeping as well. You don't sleep as well. You don't get the same deep sleep. I can tell. Yeah. Just one glass of wine can fuck you up a little bit. Yeah. Yeah. And that – for me, that hit in middle age. Like before that, it wasn't a problem. But now, yeah, like two drinks – two does seem to be the cutoff where life functions normally still.”

“Somehow. But I wonder if it's the timing of when you're drinking. So I wonder if you have like a glass of wine at dinner at like 6 o'clock but you don't go to bed till midnight. I wonder if then your body has a chance to process it and then you're OK. Well, the Italian style, right?”

“Like if you're not, so if you do it earlier, then you're, if you're, if you're, if you're having wine at dinner and then you've still got a few hours, alcohol is probably out of your system by the time you get to bed. The only thing you don't want is to time it so that, that the activating part of the alcohol being out of your system, is it when you're going to bed?”

“And I've had a number of patients come in thinking like, well, I used to, you know, I used to drink some wine before going to bed and I thought that would mellow me out. And then I looked at my wearable data and realized it made my sleep crappy. It made my sleep terrible. And so I stopped. Um, and so getting that feedback can sometimes be helpful.”