“in control. And also make sure you touch into the beauty of really good things. Well, I find that when you do the things that suck, you do the hard workouts and the sauna and the cold plunge, life just seems more beautiful. It really does because you're not overwhelmed with this just existential dread that just hangs over you”
“And those very difficult things do make the rest of your life easier. It's like we were talking about getting shit for cold plunges. I don't know if I get shit for talking about cold plunges. But anybody. Who doesn't think you should cold plunge hasn't cold plunged.”
“And if you stack those up throughout your day, diet, nutrition, sunlight, exercise, all these different things, cold plunge sauna, your life's going to be better. Wait. And I think a thing like martial arts, particularly jiu-jitsu, is a great addition to that. And if you don't like that, yoga is another great addition.”
“balancing act that you have to acknowledge. It's interesting how the two things that really seem to, you know, catch fire out there were the idea that cold plunges block hypertrophy and strength adaptations, if done in the six hours after weight training, but you can do it before.”
“If they were to do a couple things in the morning, view bright light, ideally from sunlight, I've talked about these things before. Cold shower or cold plunge, 30 seconds, right? Just uncomfortably cold, then get out. Exercise of some sort that's high-intensity interval training or lift some weights that are heavy for them, that kind of thing for”
“me like, hey, man, my knee, is this BPC-157 stuff going to work? And I go, I don't know. You can try it. I know some clean sources of it. And then they'll come back a week later and like, why isn't anyone selling this, studying it, talking about this?”
“They're genuinely interested in helping people. You see two, it's two camps. So when I hear people saying, oh, yeah, this BPC, no trials, okay. Are there any adverse events we need to know about? Not that I'm aware of. And Abud says, you know, the lethal dose is like super high.”
“And I like, yeah, put two injections of BPC, gone, gone. Now, could I put saline in there and it would have been the same? Maybe. But all I know is it's gone.”
“me with chronic fatigue? Should I be taking BPC? You know, people will ask these questions. I'm thinking, well, if these people are asking the question, that means people around them are asking it. It's starting to become okay-ish to have these conversations.”
“he can kind of see the picture now. Yes, insulin's a peptide, it came from the body, but all these peptides now pharma companies are like, what is the body making? Like in the case of GLPs, when you increase GLPs twofold, fourfold, you can see some relief from type 2 diabetes, some, but not much weight loss.”
“One of the things that the GLPs and peptides and physicians and the culture around medicine has really evolved to is that in recent years, people have realized, oh, you know, these GLP drugs are expensive. They have side effects. People are micro-dosing them. They're sharing them.”
“They have a reason to be pissed and scared. Like this is their big blockbuster drug, right as all the other GLPs come off protection from generics. They're all moving to generics. It's such an interesting time because there's really never been a time in my life where there's been more information more readily”
“So it's the hyper-dopaminergic state, right? How much different is it than Adderall in terms of the actual effect? Oh, I mean, it's. Is it dose-dependent? Yeah, and we don't know what addicts are taking exactly, but yeah, I mean, Adderall is amphetamine, vivance is amphetamine.”
“I've never done cocaine. I've never done speed. I've never done Adderall or Vyvanse. We could talk about stimulants. And in the book, I talk about some of the newer stimulants that are still amphetamine-like, but a little bit potentially safer. Do you do anything like modafinil?”
“he's recovered from substance abuse issues. And has been sober a long time. He's not not a fan of psychedelics. He got me right reading the Bible, we can talk about this, like, you know, actually, church, and I know you've been going to church has been interesting thing, because a lot of what's in the Bible is about the dynamic tension between what neuroscientists would call top down and bottom”
“have to acknowledge your humanness, but also your human capacity to control these impulses. And I mean, that's a lot of what's in the Bible. It's not everything, but it's stories about that in many, many ways. Hence the seven deadly sins and the virtues and so on. But, you know, Eddie has been a pretty strong voice for caution in the veterans and other communities about the use of psychedelics.”
“You know, if I, I don't want to make more of like what I did in the book or what I'm trying to do in the podcast or public education, but like let's take the ice bath, for example. I've taken a lot of shit for the ice bath thing. You have too. We both know they don't like the cold. That's why they're talking about this.”
“That's why they're talking about this. But we know for certain, and I go through the data finally, putting yourself into a high adrenaline state where your body and brain are freaking out and doing that deliberately gets you better at dealing with high stress states, which in my mind is only a good thing. This should be basic training for children, you know, not young children, right?”
“Because there's no profit potential in these non-patentable medications. I mean, they used AI and other tools, of course, to find that women who had breast cancer surgery where lidocaine was used as a local anesthetic had a significantly lower rate of remission.”
“tumor growth. I'm making up a story here. But we know it's a very strong effect. Lidocaine makes people no money. So it's not going to cure breast cancer, but now it's standard practice. So where there's no huge profit margin, or let's say retitrutide, huge profit margin that they're facing.”
“Do you do anything like modafinil? I don't. I took one modafinil, couldn't sleep for two days. I'm very, very sensitive to these things. There is a drug that's approved for excessive daytime sleepiness that I took on a trip where I was underslept and I needed to work called Sunosi.”
“a way that still allows sleep. And for me, it was much gentler and felt better than modafinil or armodafinil. For me, the best thing that I've ever discovered for mitigating that feeling of being groggy with sleep deprivation is creatine.”
“Like Retatrutide is going to come out from Lilly, make them billions, if not trillions of dollars. They're working hard to protect that patent. But you can bet people who are getting prescribed real retatrutide from Lilly will be taking less and sharing it based on information they hear on the internet from the peptide community and on health podcasts because, and that scares the shit out of them.”
“But if people are taking itty-bitty bits of Retatrutide, and to be fair, if people who didn't do all the preclinical work are selling it and making profits, I understand that siphons profit away from Lily. They have a reason to be pissed and scared.”
“And it's also, I think, Sam, who's the guy who wrote A Fighter's Heart? I love that book. Sam Shepard? Sam Shepard. He also talks about like it's like an intimate thing to spar with somebody. Like, what does he say? He's like, you're sharing bodily fluids with somebody.”
“And one of the reasons why I ask is because I take these. Tucker Carlson sends me these Alps. I like these. They taste different than the other ones? I've tried athletic nicotine, Zin. I've not tried the alps. I like athletic nicotine. That's probably my favorite, like the threes, because it's mild.”
“And so you'll see people who are doing this like writhing like this. You'll see them on the street a lot. Sometimes that's psychosis. A lot of times that's psychotic people who are taking their antipsychotic medication. Yeah. But you know, it gives you some empathy. And tell the voices to shut the fuck up.”
“Tucker Carlson sends me these Alps. I like these. They taste different than the other ones? I've tried athletic nicotine, Zin. I've not tried the alps. I like athletic nicotine. That's probably my favorite, like the threes, because it's mild. Yeah. The little three milligrams. My point is, I do it all the time.”
Also filed under Nicotine Pouches
“They still get all this coca leaf sent to this factory in the United States. It's still going there. And then they extract the components that they need to, put it into Coca-Cola. To this day, this happened today.”
“And for me, it was much gentler and felt better than modafinil or armodafinil. For me, the best thing that I've ever discovered for mitigating that feeling of being groggy with sleep deprivation is creatine. That definitely helps. The data on creatine for strength are there.”
“For some people, it's compulsive water drinking. I mean, Anna Lemke of Dopamine Nation talks about a patient of hers that was basically addicted to water, a compulsive water drinker. They actually died. It's very, very sad. Like, in all seriousness, like over ingestion of water in this woman.”
“Turns out it's the synthetic kratom product that is bad, highly addictive. So when you have those drinks, like what is it, Live-free? Aren't those, is that the kratom synthetic or is that the plant? I think it's the plant-derived isolated kratom, which is somewhere in between the two.”
“Take a lot of glutathione, mitigate whatever you're doing to your body by actually consuming alcohol. And more likely, you don't need as much as you're going to drink. That's the problem. But to have a good time, a couple drinks, you have a good time.”
“worse, is that for the longest time, we thought that dopamine, too much dopamine was schizophrenia. Why? Because drugs that reduce dopamine, we call them neuroleptic drugs, haloperidol, all these things, Clozapine would reduce auditory hallucinations. So the conclusion was... Auditory.”
“And I do sometimes during the day, like I'll wake up in the morning and say, I'm not going to eat them today. I'm not going to take any nicotine pill. But I always wonder, like, is it just I got lucky? Like, some people, they literally cannot drink. Alcoholism is in their genetics. Like, they have families that are alcoholics.”
“a long time ago. They gave me Vicodin. I took half of one. I never wanted that experience again. You know, but I know people who are like Vicodin. They love Vicodin. They love being sedated. They like being sedated. They like being brought down a bit in terms of arousal. Some people like being ramped up.”
“I get tenure at Stanford. This kind of shit is happening in my science world. Then a colleague of mine gets addicted to OxyContin after a back injury, and he's dead. And no one talks about it. Like everyone's like, oh, yeah, yeah. He was a member of the National Academy. He's a famous scientist down at the Salk Institute.”
“That's smart. And it just segregates things nicely. If people send me stuff, I send it to that phone and then I look at it. I have a lockbox, like a Supermax prison lockbox for my phone. That's how I wrote that book. It was gnarly. I mean, like, you know, I'm good at putting ass to chair, as they say, and just working.”
“And then all the, you know, people are thinking about biohacking with this as well. There's Pinealon, which I'll occasionally take and you get three hours of REM sleep that night. And on subsequent nights, your REM sleep is enriched. Interesting.”
“It's not specific to one neuromodulator. And if you give somebody propranolol, a drug that blocks the receptors that adrenaline binds to after learning, they won't learn as well. You can't remember stuff.”
“I mean, I have multiple examples of this. There's a great study out of WashU, and this is wild, where they compare Ritalin and other stimulants, but mostly Ritalin, to a good night's sleep for kids' ability to focus. It turns out these kids with ADHD taking these drugs, what they're really getting is the equivalent of a good night's sleep.”
“It was wild. There's a great book. It's very dense, but it's called The Prince of Medicine. It's all this medieval stuff that you love. And you'll realize what a prehistoric thing medicine is even now. Like how fast and how far we've come in the last 50 years, 100 years.”
“do whatever the government says, unless it's this government, like that, that kind of mindset, who are saying like, oh yeah, would low-dose Tirzepatide help me with chronic fatigue? Should I be taking BPC?”
“But this dude, I have him running on the fucking treadmill in the morning. Oh, wow. Oh, yeah. I take him for a walk, and I've trained him from the time he was nine weeks to run on the treadmill. Does he like it? He fucking loves it. He'll haul ass it. Like right now, he's up to five on a two incline, and he's just like at the back of that thing.”
“They like Vicodin. They like opioids. I had a tooth surgery a long time ago. They gave me Vicodin. I took half of one. I never wanted that experience again. But I know people who are like Vicodin. They love Vicodin. They love being sedated.”
“Yeah. And we don't know what addicts are taking exactly, but yeah, I mean, Adderall is amphetamine. Vyvanse is amphetamine. I actually have a, forgive me for referencing the book too many times. It'd be great if people want to read it, but that's not my goal here is to constantly reference it. But there's a long section on all stimulants, caffeine, nicotine, Adderall, Vyvanse, modafinil,”
“aspect. There's a funness to a glass of wine or, you know, a glass of whiskey. But the thing is, just understand what you're doing and don't fuck your body up and try to do your best.”
“aspect. There's a funness to a glass of wine or, you know, a glass of whiskey. But the thing is, just understand what you're doing and don't fuck your body up and try to do your best.”
“And I've been drinking, I've been drinking a shit ton of caffeine. I mean, I've got a picture. I'm half Argentine. So there's a picture of me on my grandfather's lap drinking mate from a gourd when I'm like three years old in my Spider-Man pajamas. You know, people on the internet, they go, oh, I don't believe, I'll probably drink 800 milligrams of caffeine a day, and I'm fine.”
“Tucker Carlson sends me these Alps. I like these. They taste different than the other ones? I've tried athletic nicotine, Zin. I've not tried the alps. I like athletic nicotine. That's probably my favorite, like the threes, because it's mild. Yeah. The little three milligrams. My point is, I do it all the time.”
Also filed under Nicotine Pouches
As referenced on air, with the quote and the moment. Reported, not evaluated.
“I know of at least three clinical trials looking at MDMA at dosages that are by body weight, but that are not like outrageously high dosages that have people move through their PTSD within a matter of four to six weeks total.”
“there's actually a paper. I hate this paper, but it's a real paper that like watching zip popping like stimulates dopamine.”
“The key discovery of those guys, Mersenek, Rekinzone, and Kilgard that I mentioned earlier, you can give an animal or a person any molecule that will increase those, give them a learning session, and they'll learn better.”
“Larry Cahill and James McGough, people want to look it up. Beautiful literature.”