Supplements mentioned on Huberman Lab

60 supplements from the 51 episodes we have processed, ranked by how many episodes they came up in. Sponsor reads are left out. How we check

1. 2
   Alpha-GPC

   6 episodes

   “Yeah, as a milder alternative to nicotine. One advantage of alpha GPC is if you're going to work out late in the day and you need to sleep a few hours later, it does have a sort of quote-unquote stimulant effect, but it actually can increase the amount of REM sleep you get as opposed to mess with your sleep like a lot of stimulants.”

   Unlocking Persistent Motivation & Extreme Resilience | Ross Edgley · 26/10/2026 · at 2:04:20

2. 3
   Omega-3

   5 episodes

   “And here I'm referring to the so-called omega-3 essential fatty acids, in particular the omega-3 form of the essential fatty acids. There's now a lot of data showing that ingesting one to three grams of EPA in particular in the form of either fish oil capsules or liquid can be beneficial for a number of different aspects of brain and body health and can enhance focus and cognitive ability.”

   Essentials: Developing a Rational Approach to Supplementation for Health & Performance · 22/10/2026 · at 30:29

3. 4
   L-Tyrosine

   5 episodes

   “Like I think I get on really well with that. I find it's a nicer focus, not just kind of getting all jittery tyrosine, L-Tyrosine as a precursor to dopamine, Huperzine , and the cholinergic pathway. You're clearly illustrating a very important point, which is one that has been hard for me to get out”

   Unlocking Persistent Motivation & Extreme Resilience | Ross Edgley · 26/10/2026 · at 2:07:00

4. 5
   Magnesium

   3 episodes

   “But micronutrients play a huge role in terms of hormone production. Magnesium is hugely involved in the way that you get rid of estrogen, as an example. So micronutrient testing, what I usually do is a combination of blood and urine. And so I'm looking at all of the micronutrients that we can measure that have some clinical scientific basis behind them.”

   Essentials: How to Optimize Female Hormone Health for Vitality & Longevity | Dr. Sara Gottfried · 13/08/2026 · at 4:48

5. 6
   Fish Oil

   3 episodes

   “fish oil capsules or liquid can be beneficial for a number of different aspects of brain and body health and can enhance focus and cognitive ability.”

   Essentials: Developing a Rational Approach to Supplementation for Health & Performance · 22/10/2026 · at 30:54

6. 7
   Garlic

   3 episodes

   “So ingestion of particular food compounds actually can increase TMAO, is to offset that by taking 600 milligrams of garlic. Now, I've been taking alpha GPC pretty consistently for a number of years.”

   Essentials: Tools to Improve Your Focus & Concentration · 01/10/2026 · at 34:32

7. 8
   Vitamin D

   3 episodes

   “You want to find a deficit and then supplement, right? So, even with vitamin D, you know, most people probably are deficient, so they benefit from it, but there's no point in really doing it unless you're deficient for most things. And I think with omega-3s, it's similar. You want to get your daily allowance, if you will.”

   Best Tools for Gut Health & Weight Loss | Dr. Chris Thompson · 21/09/2026 · at 2:04:08

8. 9
   EPA

   3 episodes

   “There's now a lot of data showing that ingesting one to three grams of EPA in particular in the form of either fish oil capsules or liquid can be beneficial for a number of different aspects of brain and body health and can enhance focus and cognitive ability.”

   Essentials: Developing a Rational Approach to Supplementation for Health & Performance · 22/10/2026 · at 30:40

9. 10
   Myo-Inositol

   3 episodes

   “might want to consider. The first is myoinositol, typically taken as 900 milligrams of myoinositol. Other people who wake up in the middle of the night will wake up because their dreams are very intense. Those people would do well to avoid certain supplements.”

   Essentials: Developing a Rational Approach to Supplementation for Health & Performance · 22/10/2026 · at 10:53

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